Journal of Cheminformatics will only publish research or software that is entirely reproducible by third parties. This means that any datasets, software and algorithms that are required to reach the conclusions stated in the paper must be provided as supplemental materials, or be otherwise accessible without the need for registration, login or agreement with license terms other than Creative Commons licenses for data and text and OSI-approved Open Source Licenses for software. For any software, the source code must be provided.
Methodologies should present a new computational method, test or procedure. The method described may either be completely new, or may offer a better version of an existing method. If the latter, the article must describe a demonstrable advance on what is currently available. The method needs to have been well tested using appropriate validation methods (for example, by comparison to a null model, using appropriate statistics and so on). Ideally, experimental validation of the computational method should be provided, but this is not a requirement.
A graphical abstract can be supplied which, together with the article title, should provide the reader with a visual description of the type of chemistry covered in the article. The graphical abstract should be 920 x 300 pixels and a maximum of 150KB jpeg, png or svg file. Authors are encouraged to make judicious use of colour in graphical abstracts. All graphical abstracts should have a white background and where possible should fill the available width.